Research
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Medical Research Funded & Supported by NCCS
Following is a list of medical research grants in neuroblastoma children’s cancer that have been funded and supported by the Neuroblastoma Children’s Cancer Society.
- 2020 $35,000 Grant in support of “International Neuroblastoma Risk Group (Pediatric Cancer Data Commons*)- University of Chicago (Dr. Sam Volchenboum).
- 2019 $35,000 Grant in support of “International Neuroblastoma Risk Group (Pediatric Cancer Data Commons*)” – University of Chicago (Dr. Sam Volchenboum).
- 2018 $30,000 Grant in support of “International Neuroblastoma Risk Group (Pediatric Cancer Data Commons*)- University of Chicago (Dr. Sam Volchenboum).
- 2017 $25,000 Interactive International Neuroblastoma Information Network
- 2016 $25,000 Interactive International Neuroblastoma Information Network
- 2015 $25,000 Interactive International Neuroblastoma Information Network to be co-directed by Drs. Susan Cohn, Eneida Mendonca, and Wendy London.
- 2014 $30,000 Interactive International Neuroblastoma Information Network to be co-directed by Drs. Susan Cohn, Eneida Mendonca, and Wendy London.
- 2013 $50,000 Interactive International Neuroblastoma Information Network to be co-directed by Drs. Susan Cohn, Eneida Mendonca, and Wendy London.
- 2012 $50,000 Interactive International Neuroblastoma Information Network to be co-directed by Drs. Susan Cohn, Eneida Mendonca, and Wendy London.
- 2011 $55,000 Interactive International Neuroblastoma Information Network to be co-directed by Drs. Susan Cohn, Eneida Mendonca, and Wendy London.
- 2010 $50,000 Neuroblastoma Research Grant awarded to Dr. Susan Cohn at the University of Chicago Comer Children’s Hospital
- Anti-angiogenic SPARC peptides inhibit progression of neuroblastoma tumors
- Epigenetic arnticeletic alterations differ in phenotypically distinct human neuroblastoma cell lines
- 2009 $50,000 Neuroblastoma Research Grant awarded to Dr. Susan Cohn at the University of Chicago Comer Children’s Hospital
- Presence of cancer-associated fibroblasts inversely correlates with Schawnnian stroma in neuroblastoma tumors – Modern Pathology
- 2009 $50,000 Neuroblastoma Research Grant awarded to Dr. Wendy London (Children’s Hospital, Philadelphia) and to the University of Chicago Comer Children’s Hospital
- Neuroblastoma Virtual Tumor Bank
- 2008 $60,000 Neuroblastoma Research Grant awarded to Dr. Susan Cohn, at the University of Chicago Comer Children’s Hospital
- The International Neuroblastoma Risk Group (INRG) Classification System: An INRG Task Force Report – Journal of Clinical Oncology
- 2008 $50,000 Neuroblastoma Research Grant awarded to Dr. Robert Seeger at the Children’s Hospital Los Angeles
- Neuroblastoma Genomic Signatures Predict Survival of Patients
- 2008 HR 1553 Legislation passed
- Caroline Price Walker Conquer Childhood Cancer Act
- 2007 $65,000 Neuroblastoma Research Grant awarded to Dr. Susan Cohn, at the University of Chicago Comer Children’s Hospital
- 2007 $50,000 Neuroblastoma Research Grant awarded to Dr. Katherine Matthay, Leader of the NANT Consortium”
- New Approaches to Neuroblastoma Therapy (NANT) Consortium Phase I and II Clinical Trials
Year to date, NCCS has given over 2 million dollars to fund Neuroblastoma research since its inception.
*Pediatric Cancer Data Commons
University of Chicago – Dr. Sam Volchenboum
Connect. Share. Cure. – Pediatric Cancer Data Commons (uchicago.edu)
International Neuroblastoma Risk Group Data Commons (INRG)
University of Chicago – Dr. Susan Cohn among others
INRG – Pediatric Cancer Data Commons (uchicago.edu)
The INRG task force has established a database containing information on over 22,000 children with neuroblastoma from around the world. These data are available to investigators from around the world for data mining studies, and significant discoveries have already been made using this unique resource.
The amount of data continues to expand, as the cooperative groups have agreed to update existing patient data and add new patient data once clinical trials are completed and the objectives of the trial are published. In addition, efforts to add data on relapsed patients as well as new genomic data including ALK mutations and segmental chromosomal aberrations are ongoing. Radiographic and pathology imaging data will also be uploaded in the future. The architecture housing the database has been transformed to a new web-based system with technology that enables linkage with other databases. This new ecosystem, the INRG Data Commons, has enabled the connection of the phenotype data to the Children’s Oncology Group (COG) Biopathology Center at The Research Institute at Nationwide Children’s Hospital that contains banked neuroblastoma tumor tissue from COG patients. Links to genomic data in GEO and TARGET have also been established.
In addition to clinical information, investigators are now able to determine if banked tumor tissue or genomic data are available for research studies on specific cohorts of patients. We anticipate that the INRG Data Commons will facilitate international, multi-institutional, interdisciplinary research in childhood neuroblastoma, advance our understanding of the pathogenesis of this neoplasm, and ultimately lead to the development of more effective treatment strategies for children with neuroblastoma.
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